ENJOY IN LIFE

Archive for the ‘Lifestyle’ Category

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Lifestyle drugs have been a much debated segment of therapeutics for the pharmaceutical industry primarily due to the issues surrounding their inclusion in drug payment plans and diversion of resources for their research. These drugs have been a point of contention also because of a lack of clarity in defining them. For the purpose of this report, lifestyle diseases have been defined to include a range of indications that affect an individual’s quality of life even though they may not be deemed a medical problem.

The market was led by the MDD therapeutic segment followed by hormonal contraceptives. The smallest indication among the lifestyle disorders was alcohol dependence. The overall market was .2bn but is forecast to decline, albeit with a low single digit CAGR over the 2008-14 period.

Lifestyle disorders are marked by slowed R&D process and limited investigational products though MDD reflects some differences to this scenario. Each of the therapeutic indication s considered in this report reflects a markedly different scenario that substantiates the investment case around them. For instance:

• In the antidepressants market , the older antidepressants such as tricyclic s and monoamine oxidase inhibitors, have given way to agents that target metabolism, storage and release neurotransmitters such as serotonin and norepinephrine.
• In case of obesity, compounds with novel mechanisms of action such as GLP-1 pathway, monoamine transmission, PTP-1B receptor and melanin system, are being investigated.
• The hormonal contraceptives market is marked with little R&D that has led to gaps in contraceptive technology. The industry needs to invest in contraceptives with better side-effects profile to aid compliance.
• In the smoking cessation market, growth prospects of the leading brands such as Pfizer’s Chantix, are likely to be determined by the market’s response to the black box label warnings on neuropsychiatric effects, introduced in July 2009.

Key features of this report

• Epidemiological analysis of the therapeutic segments and forecast prevalence over the period 2008-14
• Forecasts and analysis of the key products in the lifestyle disorders market over the period 2008-14, across major classes of treatments
• Overview of key events in the global lifestyle disorders market that have impacted treatment trends and sales potential.
• Strategic and growth analysis of leading pharmaceutical corporations based on sales focus by drug class, currently marketed products and R&D product portfolios
• Detailed analysis of the major classes of treatments across all the therapeutic segments analyzed in the report
• Detailed analysis of the clinically differentiated products in the lifestyle disorders market pipeline and sales forecast of key R&D pipeline products in the global lifestyle disorders market

Scope of this report

• Develop insights into patient potential with the report’s coverage of the therapy area and leading lifestyle disorders players today.
• Quickly understand how recent events are affecting the performance of major products and how leading players are confronting competitive challenges in the lifestyle disorders marketplace.
• Gain up-to-date market intelligence across the lifestyle disorders category and understand the major issues affecting key pharmaceutical marketers.
• Understand which drug classes have the greatest potential to drive lifestyle disorders franchise growth, and how pharmaceutical companies are attempting to capitalize these market opportunities.
• Compare the franchises of leading pharmaceutical marketers across key therapeutic classes and understand how market share of leading companies will evolve over the next six years.

Key Market Issues

• Reimbursement of lifestyle drugs replete with challenges
The reimbursement of lifestyle drugs is a much debated subject in most nations. This is primarily because most lifestyle disorders tend to be non-life threatening.
• The global contraceptives market – slowed R&D
Use of contraceptives has increased across different categories of women population and across geographies as well. However there is still need for further market penetration of contraceptives. The key concerns that women tend to have are the actual and perceived side effects of their use. From the industry front, there is little R&D in this therapeutic category that has led to gaps in contraceptive technology.
• CNS side-effects limiting the growth of smoking cessation products
Sanofi-Aventis terminated the development of its smoking cessation product Dianicline citing reasons that it was not differentiated adequately from Chantix. As the drug has the same mechanism of action as Chantix, the likely CNS side-effects made it less attractive. In July 2009, the FDA had added black box label warning on neuropsychiatric effects on Chantix and Zyban labels, which is likely to impede their growth over the forecast period.

Key findings from this report

• The R&D pipeline for lifestyle disorders shows a lot of variation across indications. For conditions such as MDD, there are several compounds under different investigational stages (both early and late) while indications such as alopecia reflect slowed R&D process.
• The antidepressants market R&D has been evolving and newer therapies have been emerging. The older antidepressants gave way to agents that target metabolism, storage and release of neurotransmitters such as serotonin and norepinephrine. The newer antidepressants such as SSRIs and SNRIs have a much better safety and side effects profile and have taken precedence in the less severe depression market.
• The global contraceptives market presents opportunities for companies to invest in considering the little R&D in this therapeutic category that has led to gaps in contraceptive technology. There is much scope for the industry to invest in contraceptives with better side-effects profile to aid compliance.
• Three closely-watched obesity drugs are currently under development – Arena Pharmaceuticals’ lorcaserin, Vivus’ Qnexa and Orexigen Therapeutics ‘Contrave . With few drug options in the obesity market, any approval would mark the first new obesity drug to enter the market in ten years.

Key questions answered

• Which companies were the leading players in the lifestyle disorders therapy area in 2008?
• How have recent major launches from the key market players performed?
• Which companies will become the key players in the lifestyle disorders market over the period 2008-14?
• Which products will be impacted by generic competitors over the period 2008-14?
• Which pipeline products are expected to generate sustainable revenue growth?

I have a different theory that I’m confident will not be popular with men, however; I think if there was a private focus group with Christian women and they were asked to be honest, my hypothesis would prove correct.  A lot of men trying to live the Christian Lifestyle are TO SOFT.  Yes I said it, too soft, too timid, and struggle in their identity and behavior.  And look I’m not saying this as though I’m immune from the experience. When I first made the transition from being a “fornicating fool” to living a Christian Lifestyle it was very difficult figuring out how to reprogram myself in a way that didn’t go from one extreme to the other.

What would make a difference with a lot of men would be if we were to truly study Christ and fill in some of the missing blanks.  For instance, Christ was bold, humorous, and commanding, while being humble and holy.  That is the balance that we as Christian men have to have.  Women, Christian or not have a few characteristics if men they are looking for that stay consistent.  Women want men that are leaders, that can make them laugh, that can be compassionate and stern at the same time.  The Christian Walk shouldn’t make you lose or pull back on any of these characteristics.  What ultimately ought to change when becoming a Christian male is the goal of your interaction with women and an increase in respect level.

Being a fornicating fool my objectives were clear, to get a woman to engage in physical activity with me.  I would say what I needed to say, do what I needed to do, with that very singular focus in mind.  I did it very well.  Starting the Christian Walk, the objectives changed to being respectful of every woman, having interactions that are friendship based, and being able to discriminate and find that one woman that you can potentially spend the rest of your life with.  Doing this without getting physical; I think too many Christian men think to themselves since it is a sin to get physical then I have to be completely stand offish.  That what women are looking for men who are timid, that is not the case.  You’ll find yourself being “the friend”, the nice guy that gets purely the “church hug” and watches as the woman he’s attracted to ends up with the next guy.

Instead, I encourage men to work on being more humorous, to even being slightly sarcastic, to shift focus from taking a woman out being a restaurant to instead making it about having them accompany you to the grocery store, or meeting them at star bucks.  The most important thing with women is having good conversation; a woman is constantly testing and filtering in a way that we don’t even comprehend.  It is much easier to break through those barriers and hurdles if you are in a conversational setting versus the traditional “date setting.”

Finally guys, if you show signs of your interest, but do not come across as “pressed.”  This sends wonderful vibes to women; it communicates confidence in more of a way than anything else you would do.

Survery says that 52% of  Women Complain About  Having a Bloated Belly

A new survey which was recently published on In2town Lifestyle Magazine, which was commissioned by Activia has revealed a bloated belly as the number one body complaint amongst British women with 52% of women surveyed stating that they would rather live without it. Lower belly bloating or LBB (described in the survey as the physical increase in below the waistband belly size) has even overtaken other irksome conditions such as the muffin top and ‘cankles’ (thick ankles), not to mention more visual features such as a double chin, little boobs or ‘thunder thighs’.

Move over Muffin top, LBB tops the poll…

1. Lower Belly Bloat (LBB) (52%)
2. Double chin (42%)
3. Thunder thighs (41%)
4. Muffin top (31%)
5. Back fat (23%)
6. Small breasts (11%)
7. Cankles (6%)

The research, launched to highlight the misery brought by even a mild digestive disorder, showed almost ¾ of British women (over 20 million) to be afflicted with LBB, at some time in their lives, with 80% having to regularly perform the obligatory, yet embarrassing ‘trouser tummy tuck’ i.e. having to pull their waistband up and over their bellies when sitting down. Hardly surprising when you consider that LBB can result in an increase in waist circumference of up to 12cm over the course of a day.

Claire Hegarty a leading Health Expert who deals with Weight Loss Hypnotherapy and Irritable Bowel Syndrome Therapy, said: “This survey does not surprise me. A women’s mood changes when she is bloated and she sees herself in a different light when she tries on clothes that look different because she is bloated. Women tend to worry more about how other people see them and although some men do as well, it is more in common with women and that is why women are concerned when they feel bloated.”

Although abdominal bloating can frequently be a result of lifestyle and stress, it is also thought to possibly be as a result of slower ‘transit time’ – where food doesn’t move through the system as quickly as it could. Corinne Chant, Activia’s Marketing Manager, says: “Activia is scientifically proven to help improve slower digestive transit,* with 82% of people with self-reported digestive discomfort saying that they felt better after having Activia for two weeks, and 87% reporting that they feel less bloated. “

At one point or another every guy wants to know how to attract young women.  Young women have an energy and viewpoint that makes you feel invigorated and more alive.  Plus, they’re just plain fun.  They’re will to try new experiences and go new places just for the fun of it.  

If you’re a guy of in his late twenties to mid-thirties, knowing how to attract young women is a lot easier than you realize.  The first thing to know is that they’re already attracted to you because you ARE older.  Not too old, just old enough that they see that you’re no longer a boy that they have to coddle or share expenses with.  You’ve got some maturity under your belt and that’s extremely sexy.

Young women love to feel a variety of emotions.  Many of them are tasting independence for the first time in their lives, and they love it.  If you’re going to attract young women you need to be aware that they are enjoying the adventure of dating an older man, but they want that man to be able to have fun and share in her emotions.  

The easiest way to do that is to have conversations about things that she can relate to. It doesn’t matter if it sounds silly to you.  If it’s fun for her, then talk about it.  Attract young women by talking about their pets, their interests, and the types of things they find humorous (this can be anything from cartoons to hip comedians).  Talk about these types of subjects for a couple of minutes at a time, and then switch to another topic.  Switching around topics is a fairly easy way to make the conversation have flow and energy.

Energy is another good way to attract young women.  Adapt your lifestyle to a more energetic, physical lifestyle.  Young women like physical activity; they like to play.  If you play a game of soccer, or go to yoga, or even toss a Frisbee around the park, this stimulates the feel-good endorphins in both of you.  Then, play becomes just another word for foreplay.  

I’m not saying that you need to change who you are to attract young women.  On the contrary, you’d be cheating both yourself and her if you don’t let her get to know who you really are.  I’m stating that you need to be flexible and adapt to a younger lifestyle.  

You’ll find that dating young women is a total blast and boost to your ego.  Once you go through the process to attract young women the first time, then you’ll have no problem meeting, dating, and having sex with young women from now on.  

If you would like to watch a FREE VIDEO of me approaching attractive women in the real world, starting interesting conversations, creating attraction and getting phone numbers and dates, then watch the free video here now: http://www.SucceedAtDating.com.